Possible Clues:

• Autonomous region of Spain
• Home to Henry VIII's Catherine
• Catherine of ...... was first wife of Henry VIII
• Ferdinand II's realm
• Ferdinand II of ____ and Isabella I of Castile were Spain’s “Catholic Monarchs”
• Catherine of --
• Home of Henry VIII's first wife
• One of Isabella I's kingdoms
• Head falls off superb example from part of Spain
• Whence Henry's Catherine