Possible Clues:

• See 1-Down
• Go ___ (turn in)
• Where people who retire go
• Where editors put the paper
• Words repeated by Lady Macbeth in Act V, Scene 1
• Phrase said five times by Lady Macbeth soon after 'Out, damned spot!'
• Words with go or off
• 'And so --'
• 'And so ___'