Possible Clues:

• Enemy organization in Marvel Comics
• Legendary monster depicted in filthy drawing
• Greek monster with nine heads
• Creature slain in the second labour of Hercules
• Big serpent in flowery bushes up to the middle
• Newsworthy drama involving Greek island
• Hardy (anag) — persistent trouble with many aspects
• Hardy hero holds up many-headed monster
• Losing case, The Yard cracked persistent problem
• Stars taking part in noteworthy drama