Possible Clues:

• The ultimate brew: Murphy's Original Stout
• Greatest possible number among stout characters
• Ultimate extremes of upset doctors treated originally
• Foremost of universities? To many, Oxford seems the greatest
• Best
• At furthest limit
• How you got tea so little, more than more
• Furthest or maximum possible
• Furthest or extreme
• Note way crime's committed - way is extreme