Possible Clues:

• Most unpleasant
• Tops in turpitude
• It's a very unpleasant way to turn up in a nest
• How most unpleasant to be like ties inside
• Extremely unpleasant wine found in pleasant home
• I sat there with the eggs in a very unpleasant kind of way (8)
• Most malicious
• Might this get a saint set to be most unpleasant? (8)
• Wine stored within the home is most unpleasant
• Most unpleasant wine brought into home