Possible Clues:

• Might 27 down have been so horrible about Reg's inside?
• She would be horrible enough to gore the ship
• Gee! How horrible she is in those sores
• In such a gross setting, 'e makes 'er gross
• Terrifying woman
• Bad witch, e.g.
• Female fairy tale baddie
• Gee! With the roses around, she's no good at all (6)
• Monstrous female heads off advance
• How horrible for her to be so gross around the East! (6)