Possible Clues:

• John of the "Harold & Kumar" films
• “Cowboy Bebop” star John
• John of "Harold and Kumar" films
• 'Searching' actor John
• 'Assassin' comedian Margaret
• 'Cowboy Bebop' star John
• Comedian Margaret whose surname is hidden in "Watch out!"
• Actor John who plays Sulu in "Star Trek" films
• Margaret who lampooned Kim Jong Il
• Margaret who officiated weddings during a 2015 comedy tour