Possible Clues:

• R-rating reason
• It often involves insertion
• Marcy Playground: "___ and Candy"
• Word with safe or fair
• Word with appeal or change
• 'God's joke on human beings': Bette Davis
• Box marked "M," "F", or "Yes, please!"
• Rolling Stones "___ Drive"
• VI (Lat.); m. or f.
• It requires you to choose a position