Possible Clues:

• Colombian Town
• City that a 10-Down might live in
• Southern Hemisphere metropolis containing the Plaza de Caicedo
• Colombian city considered the capital of salsa
• Biggie "Going Back to ___"
• Where LL Cool J is 'going back to,' according to a 1989 rap jam
• City famous for bad traffic?
• Infamous city of Colombia
• Colombian city of two million
• Colombian city, capital of the Valle del Cauca