Possible Clues:

• Blue -- not quite up
• Thoroughly blue
• 'Unhappy, sorry (3)'
• Replete with regret
• 'Unhappy, down (3)'
• 'This, you see, may he brew with depression, maybe (3)'
• Mentioned one being put out and far from happy
• Unlike a good excuse
• Needing a hug, maybe
• Too bad the old man's standing on his head