Possible Clues:

• You might calmly tell someone not to do this
• 'Hattie Harmony: ___ Detective' (kids' book by Elizabeth Olsen and Robbie Arnett)
• Expressing sympathy with wife taking out small dog
• Brood keen to leave New Yorker
• 'Don't You ___ 'Bout a Thing' (Stevie Wonder hit)
• Cause of a furrowed brow
• 'Don't ___, Be Happy'
• Bother
• 'What, me ___?': Alfred E. Neuman line
• Lose sleep or fret