Possible Clues:

• Classic Clapton song
• Girl in an Eric Clapton song
• Clapton woman who's "got me on my knees"
• Hit for Derek and the Dominos
• Rock classic with the lyric "Darling, won't you ease my worried mind"
• Classic sung by Eric Clapton
• 1972 top 10 hit that was over 7 minutes long
• "___, you got me on my knees" Clapton
• Clapton smash
• Grammy-winning Eric Clapton tune