Possible Clues:

• Lacking in sensitivity, gossip sums up Jack's career with vocal exchange
• Medical term for a general loss of feeling in part of the body
• Loss of feeling
• Number Ten has ruined European continent's housing
• Lack of feeling in these as a criminal follows American
• Loss of bodily sensation caused by nerve damage
• Loss of feeling through administered drugs
• Insensitivity to pain induced by drugs
• Drug-induced insensitivity to pain
• The loss of feeling that can affect NHS patients?