Possible Clues:

• Hard-hearted one's lack
• 'That's a shame!'
• 'I ___ the fool ...' (Mr. T line)
• Sympathy and sorrow
• "That's a shame!"
• 'Alas!'
• Shame city centre's controlled by party extremists
• Shame -- mine must come before the start of yours
• 'Too bad'
• Wilfred Owen's subject: 'War, and the __ of War'