Possible Clues:

• US city street in financially favourable situation
• Way to plug advantage in Tea Party location
• City where the Globe is published
• Big city in Massachusetts
• American city whose local teams won the Super Bowl and World Series in 2004
• Massachusetts metropolis
• Site of a famous marathon
• Capital founded in 1630
• East Anglian town that's 'stumped' (stumped in time of prosperity)
• Home of the oldest active M.L.B. ballpark