Possible Clues:

• With 41 Across, rout
• See how skinny it is if it's 22 acrossed
• Free from contamination - entirely
• Frisked without incident
• Scour
• Clank, perhaps, with the help of soap
• Pure; fresh
• Family taking ecstasy, yet free of drugs!
• See 19
• This perhaps was before he'd made it like this to incline after the century