Possible Clues:

• Sort of disease treated by district nurses?
• Native to a particular region
• Characteristic of a particular area around Clare containing denim production
• Native to a region
• One leaving medicine out in local
• Regularly occurring, disease say
• It's always therte to kill mice by getting them in pieces
• Prevalent in a district - dice men (anag)
• Regional
• Confined to a particular area