Possible Clues:

• Spanish inquisitor
• Spanish cardinal, statesman and Grand Inquisitor
• The pseudonym of the crossword setter D S Macnutt
• Pseudonym of the crossword setter D.S. Macnutt
• Spanish inquisitor - or a pioneering Observer crossword setter
• Spanish grand inquisitor
• 5 across imprisoning opponent, not entirely upstanding as 5 across
• Grand inquisitor and cardinal rising, inspiring people with energy
• Spanish grand inquisitor; see minx (anag.)
• Stir about new living in diocese recalled by fearful cardinal