Possible Clues:

• It could be a 7th century pope
• Cocktail of vermouth and gin or vodka
• James Bond's drink of choice
• Type of Italian vermouth
• 'When 'arf of your bullets fly wide in the ditch / Don't call your — a cross-eyed old bitch' (Kipling, Barrack-room Ballads)
• Simone --, Italian painter (c. 1284-1344)
• Craft displayed in small cocktail
• Swallow last of Chianti, an Italian drink
• Cocktail called 'the elixir of quietude' by 4-Down
• Drink, or where you might buy trendy one