Possible Clues:

• Solitude of drink -- Venetian dismissing outsiders in bar ...
• Sense of isolation — less online (anag)
• Desolation
• Isolation unit needed in outbreak of illness
• Left single, poetry beginning to sharpen this?
• 2003 single by Tomcraft which reached No 1 in the UK charts
• Mixing online less creates isolation
• Isolation
• Awful illness overshadowing one's solitude
• Penned in doggerel, one line's spreading sad feelings