Possible Clues:

• Many a '?' clue in a crossword
• 'Ugh, German sausage is the wurst,' e.g
• Many a New York Post headline
• Many a bon mot
• Feature of many a Ludacris lyric
• "My bike won't stand up. It's two-tired," e.g
• The title of this puzzle, e.g
• "Some nylons will give you a run for your money," e.g
• "I can't ride my bike. It's two-tired," is one
• 'Poultry in motion,' e.g