Possible Clues:

• He loved it back in Avon as a child
• A place in the Spanish sun, perhaps, by river synonymous with Shakespeare set up by lover boy
• Eponymous 18th-century adventurer
• Lover's new house in Portugal
• Lover boy
• Lothario
• Ladies' man's old hospital round interrupts drink
• Isaac Brock band Ugly ___
• Don Juan's Spanish house beside river flowing west
• Lover boy's house in Florence next to river running west