Possible Clues:

• See 11
• If you're mad enough to have this you may have lost the thread of things
• If you lose the thread of thingd you may have this
• To have this one may have lost the thread
• Should be one's turn to get tight
• With this one has lost the thread of things
• Not being tight, one has lost the thread of this
• If you've lost the thread of it you're not all there
• Not tight, just dotty, and in need of some sort of a driver
• To make you tight might fix it if you were so dotty (5, 5)