Possible Clues:

• View from Mount Pellegrino
• Chief city of Sicily
• Capital on the Tyrrhenian Sea
• Capital of China — Rome, strangely?
• Drink knocked back - more rum or port
• Not so bright, second city
• Italian city's less healthy looking medic
• Sicilan capital
• Room in protected area round city
• Certain style encapsulating almost every old Italian city