Possible Clues:

• Home to Alaska's oldest newspaper
• Coastal Alaskan town
• Alaskan city that sounds like it belongs in a 41-Down
• Alaskan city hidden in "Western omelet"
• 1899 gold rush destination
• University of Alaska campus
• Gold Rush mecca
• Port in the 49th state
• Its ''Welcome to'' sign is a gold pan
• U.S. city known to some locals as Siqnazuaq