Possible Clues:

• Rum compound made out of rare fluid
• Sweetener from old Greek territory — less common, reportedly
• Rum, unusual in a sea rising
• A rare medic all but rejected sweetener
• Sugar which shares its name with a river in Guyana
• Sugar from pear — a remedy from the east
• A dreamer roughly browned off in 25 across perhaps
• Ebb of a strange sea is something sweet
• River in Guyana, or a type of brown sugar
• Looking westward, a Red Sea somewhere in Guyana