Possible Clues:

• Endless good fortune with four in charge moneymaking
• Fresh start laundered back in dirty money is well worth the investment
• Very profitable
• Profitable cure vital to be developed
• Unfinished lute I crave, needing renovation: it could be rewarding
• Successful cruciverbalist anagrammed without fancy cribs
• Large university with originality, but no energy, raking in money
• Cut a liver out -- it's financially rewarding
• Profitable, lute vicar restored
• Well-paid vicar let loose outside university