Possible Clues:

• Savvy
• See twister (anag.)
• One's accepted by diverse tweeters if shrewd
• See twister turning out with it in the city
• One way and another become criminally aware
• Savvy in one way and another
• Intimately, densely
• Like someone on the way who is savvy?
• Shrewd and wise setter gets tipsy
• Well adapted to urban life