Possible Clues:

• Suffering can start to generate work
• Setter admitted to longing for creative work
• Mental suffering can, leading to great piece of art
• Graphic art
• Gasping at the inclusion of earliest of Italian artwork
• Constable, perhaps, catching breath, an individual collared
• Creative process isn't restricted by blip?
• Artwork on the wall
• It's just not in a paying guest to produce such art