Possible Clues:

• One classification including artist, regularly annoying
• Tiresome Irish girl can start to grate
• Irish woman can start to gossip -- that's tiresome
• Bringing up to scratch, perhaps that's annoying
• Irish and French director in circle proving troublesome
• Bishop punching two volunteers can start to get tiresome
• Abrasive girl's endless score about sex
• Getting at
• Pesky
• Trying