Possible Clues:

• Conjunction or opposition
• Astronomical alignment
• Regulars deserting Soyuz by ugly appearance of new moon
• Alignment of the sun, earth and moon, e.g.
• Highest-scoring Scrabble word that doesn't use A, E, I, O or U
• Alignment of celestial bodies
• Eclipse cause
• In classical prosody, a metrical unit of two feet
• Heartless, sneaky, zany guy's opposition of three?
• Fringe characters in silly, zany and goofy line-up of stars, perhaps