Possible Clues:

• Pisa's location
• Abroad you make a survey, at last in Italy, here?
• Italian wine region
• Region of Pisa and Siena
• Cuts damaged a US city and foreign region
• Italian region whose provinces include Arezzo, Grosseto and Lucca
• Region whose capital is Florence
• Tour oddly deficient, with no time for region of Italy
• American vessel in Tilbury to empty somewhere in Italy
• Florence is the capital of this Italian region