Possible Clues:

• Drug that's smoked in a pipe
• 'Confessions of an English ___-Eater'
• Kind of pipe
• Painkiller since ancient times
• Dope in a den?
• De Quincey confessed to eating it
• More included in order for drug
• Order to import more of Italian drug
• Award of excellence without more narcotic
• Order to import more Italian narcotic